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The material in Tempurpedic mattresses should be kept dry and clean. However, not all of these mattresses have a removable protective cover to help keep them safe. If you do spill something on your mattress, you should:
1. Blot up as much of the spill as possible. Some Tempur pedic mattresses have a protective cover to help protect against stains and spills. If your mattress has a cover, you will need to remove it before blotting up the spill.
2. Let the mattress dry out thoroughly before you remake the bed.
3. Wash the protective cover, but don't dry it in your dryer. It will need to air dry.